The Library containing over 38,400 Fsp3-enriched compounds was designed, considering an increased importance of molecular complexity and presence of chiral centers in organic compounds, that rise their potential as good drug candidates and, thus, efficiently covers biologically relevant chemical space. The parameters of the Library are indicated below. To download Fsp3-enriched Compounds Library database please follow.
| Range | Average Value |
Molecular Weight | 175 – 450 | 334 |
Fsp3 | ≥ 0.45 | 0.56 |
cLogP | < 4 | 1.7 |
TPSA | < 140 Å2 | 80 Å2 |
H-acceptors | ≤ 8 | 3.9 |
H-donors | ≤ 4 | 1.4 |
Rotatable Bonds | ≤ 8 | 4.9 |
Number of Carbonaromatics | ≤ 1 | 0.51 |